Narcolepsy: Causes, Symptoms, Treatments | Sleep Foundation ~ Healthy Lifestyle

Cataplexy is a cardinal symptom as it almost always indicates that the cause of the narcolepsy is a lack of hypocretin in the brain. Sleep paralysis - the temporary inability to talk or move when waking; it may last a few seconds to minutes.The interval between symptom onset and diagnosis ranged from within 1 to 61 years with a median of 10.5 years. Multivariate analysis showed that the presence of cataplexy as one of the initial symptoms and a more recent year of symptom onset were the only factors associated with time to diagnosis.Cataplexy is a brief, sudden loss of voluntary muscle tone caused by strong emotions like laughter. Narcolepsy, a sleep disorder that is believed to affect between 135,000 and 200,000 people in the United States, is most often associated with this disease.. Cataplexy occurs during waking hours.Cataplexy Cataplexy is defined as a sudden loss of muscle tone associated with emotion. It is pathognomonic for narcolepsy, although some patients with narcolepsy do not have cataplexy. Patients often describe knee buckling, head dropping, facial twitching, jaw dropping, or weakness of the arms.Most people with cataplexy have type 1 narcolepsy, and cataplexy is the first symptom to appear in about 10 percent of narcolepsy cases. However, cataplexy can be misdiagnosed as a seizure disorder.

Factors associated with a delay in the diagnosis of

The development and severity of symptoms associated with narcolepsy vary greatly from one person to another. The onset of symptoms initially occurs one at a time; appearance of new symptoms may be separated by years, with sleepiness generally preceding cataplexy.Cataplexy is a common symptom associated with narcolepsy. We evaluated a 51-year-old female who developed symptoms of progressive daytime sleepiness with cataplexy. [ncbi.nlm.nih.gov] Cataplexy is pathognomonic of narcolepsy with cataplexy, and defined by a transient loss of muscle tone triggered by strong emotions.Start studying Psych 133- Sleep Psych-Narcolepsy. Learn vocabulary, terms, and more with flashcards, games, and other study tools.Its main symptoms are sleep attacks, nighttime sleeplessness and cataplexy, the sudden loss of skeletal muscle tone without loss of consciousness; that is, although the person cannot talk or move,...

What is cataplexy: Symptoms, causes, and treatment

Cataplexy, a symptom associated with narcolepsy, is a waking state in which muscle tone is lost, as it is in REM sleep, while environmental awareness continues, as in alert waking. In prior work, we reported that, during cataplexy, noradrenergic neurons cease discharge, and serotonergic neurons greatly reduce activity.Signs and symptoms. Cataplexy manifests itself as muscular weakness which may range from a barely perceptible slackening of the facial muscles to complete muscle paralysis with postural collapse. Attacks are brief, most lasting from a few seconds to a couple of minutes, and typically involve dropping of the jaw, neck weakness, and/or buckling of the knees.ANSWER: Cataplexy is a symptom associated with muscle weakening.Cataplexy is a sudden muscle weakness that occurs while a person is awake. Strong emotions trigger cataplexy 1. The triggering experiences are usually positive, like laughter, witty conversations, and pleasant surprise. Episodes may also be triggered by anger, but rarely by stress, fear, or physical exertion.Neuroblastoma associated with the paraneoplastic syndrome of opsoclonus-myoclonus is well-described. However, presentation with narcolepsy-cataplexy is not well-documented in the literature. Narcolepsy with cataplexy is also rare in children younger than 5 years of age.

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